Home About us Editorial board Current issue Ahead of print Archives Submit article Instructions Subscribe Login  Contact Search
SYMPOSIUM
Year : 2016  |  Volume : 7  |  Issue : 1  |  Page : 31-33

Antimicrobial activity of sugar-based semisolid polyherbal ayurvedic formulation: Chyawanprash


1 Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, New Delhi, India
2 Dabur Research and Development Center, Sahibabad, Ghaziabad, Uttar Pradesh, India

Correspondence Address:
Sayeed Ahmad
Bioactive Natural Product Laboratory, Faculty of Pharmacy, Hamdard University, New Delhi - 110 062
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2394-6555.180159

Rights and Permissions

Objective: This study evaluated the antimicrobial activity of chloroform (CHCl3) extracts of chyawanprash (Dabur India Ltd., Uttar Pradesh, India) and hydrolyzed chyawanprash against Escherichia coli and Staphylococcus aureus on nutrient agar media using cup plate method. Materials and Methods: CHCl3extracts of chyawanprash were prepared directly as well as by previously hydrolyzing with dilute HCl. Three test groups of 10, 20, and 50 mg/ml were prepared for each CHCl3extract, whereas ampicillin 20 mg/ml was used as standard group. Further, six agar plates were prepared for each group, i.e., three for E. coli and three for S. aureus. Cups were bored on each plate with the help of steel cup borer and cups on each plate were marked for identification. Extracts of different concentrations (i.e., 10, 20, and 50 mg/ml) were poured into cups and all plates were then incubated at 37°C for 48 h. After incubation, plates were observed for bacterial growth and zone of inhibition were measured. Results: Results showed that both CHCl3as well as hydrolyzed CHCl3extract of chyawanprash showed concentration-dependent antimicrobial activity. The largest zone of inhibition was observed at the concentration of 50 mg/ml of both CHCl3extracts of chyawanprash (12.7 ± 1.5 mm for E. coli and 15.0 ± 1.0 mm for S. aureus) and hydrolyzed chyawanprash (14.3 ± 0.6 mm for E. coli and 16.3 ± 0.6 mm for S. aureus). Conclusion: Chyawanprash possesses promising potential for use as an antimicrobial agent.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed762    
    Printed27    
    Emailed0    
    PDF Downloaded70    
    Comments [Add]    

Recommend this journal